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Its active form, known as reduced glutathione, works continuously to neutralize harmful substances and support normal cellular function, making it a core part of the bodys internal protection system

E-cadherin is required for metastasis in multiple models of breast cancer

For example, similar to Nutlins, MI-219 binds MDM2 and blocks its interaction with p53, leading to induction of cell cycle arrest and selective apoptosis in tumor cells 56