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Our results so far indicated that restoring the Nnt WT/WT genotype in islets with a BL/6J background suffice to restore the glucose and FCCP regulation of mitochondrial glutathione oxidation and NAD(P)H levels to a similar extent as that previously observed in BL/6N mice
DMF induces the expression of L-2-hydroxyglutarate dehydrogenase (L2HGDH) to downregulate L-2-hydroxyglutarate (L2HG) and increase global and locus-specific DNA hydroxymethylation levels
N Engl J Med 352:16851695 Ridker PM (2016) From C-reactive protein to interleukin-6 to interleukin-1: moving upstream to identify novel targets for atheroprotection
Authors: Ayesha Dias / Editor: Charlotte Davies / Codes: AC1, DC2, EnP3, GP9, PC4, PhP1, SLO11 / Published: 10/02/2026 Obesity is a global health challenge
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