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Forelimb grip strength was determined by allowing animals to clasp a suspended wire and the time to release was recorded in females [Young ( n = 8), Old Con ( n = 12), and Old mAb ( n = 15)] and males [Young ( n = 8), Old Con ( n = 10), and Old mAb ( n = 9)]

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The majority of NTHi iron requirement is fulfilled by acquisition of haem therefore compounds that restrict haem-assimilation may have higher therapeutic value than those solely targeting iron acquisition

Acetyl-CoA metabolism in cancer