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We previously showed that GIPR activity in alpha cells potentiates amino-acid-stimulated glucagon secretion in mouse islets 11 , and here we found the same interaction between hGIP and amino acids in human islets using concentrations of amino acids found in the postprandial state (Extended Data Figure 4) 11 , prompting us to ask whether tirzepatide engagement of the GIPR in human islets also enhances the effect of amino acids on glucagon secretion
10.1016/j.molmet.2016.09.005 23 FosgerauK.HoffmannT
instead it moved into the online research-chemical and cosmetic-tanning market, where it is sold as lyophilized powder to be reconstituted and self-injected
- PubMed - NCBI." [Online]
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