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Michael Greger, Chief Science Officer at NutritionFacts.org, When selecting a B12 supplement, its important to focus on bioavailability

Standard therapies can reduce pain and fracture risk but rarely reverse the underlying tissue damage

Vitamin B12 shots may not be suitable for people with a history of: sensitivity to vitamin B12 Lebers disease, which affects the optic nerve kidney problems hypokalemia (low potassium levels) deficiencies in other nutrients, particularly folic acid and iron Vitamin B12 injections typically begin to work straight away

Different Forms of Vitamin B12 Explained Vitamin B12 exists in several distinct chemical forms, each with different properties and metabolic pathways