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Proof-of-concept therapeutic treatments, which overcome the impaired R152H GPX4 activity, including selenium supplementation, selective antioxidants and a deuterated polyunsaturated fatty acid were identified
To understand the biological overlap and therefore possible therapeutic targets for PAIS such as PASC, it is also interesting to note similar clinical features in a typical major depressive disorder, (MDD) also known as immunometabolic depression [86]
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