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Use of WEGOVY for this indication is supported by a 68-week, double-blind, placebo-controlled clinical trial in 201 pediatric patients aged 12 years and older with a BMI corresponding to 95th percentile for age and sex and from studies in adult patients with obesity [see Clinical Studies (14.3) ]
PMID: 25690343
Semaglutide is contraindicated during pregnancy and should be discontinued at least 2 months before a planned pregnancy due to its long half-life
Alternative Wnt signaling activates YAP/TAZ
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