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Rising cAMP levels then activate protein kinase A (PKA), which phosphorylates calcium-handling proteins in the heart muscle
HR, hazard ratio
Patients taking tirzepatide 10 mg achieved an average of 19.5% weight loss, and patients taking tirzepatide 15 mg achieved an average of 20.9% weight loss
Alam J, Cook JL (2003) Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway
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