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Peptides are adjuncts, not substitutes
Diabetes 65(1):3443 Alonso AM et al (2024) The vagus nerve mediates the physiological but not pharmacological effects of PYY(336) on food intake
As a sympathomimetic amine chemically related to amphetamines, it works by: Stimulating noradrenaline (norepinephrine) release in the central nervous system Activating the sympathetic 'fight or flight' response Suppressing appetite through hypothalamic stimulation Potentially influencing energy expenditure Phentermine is typically prescribed as a short-term adjunct (usually 12 weeks maximum) due to concerns about tolerance, dependence, and cardiovascular effects
Cell 166 , 13241337 (2016)
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