got pregnant on tirzepatide Accidental pregnancy while semaglutide or is not proven to cause birth defects or miscarriage in humans, but animal studies show risks (growth restriction, pregnancy loss). Current Tirzepatide and Pregnancy Planning: Safety

Tirzepatide stands apart from other commonly prescribed weight loss medications due to its innovative dual mechanism of action

In this study, using pro-atherogenic ApoE-deficient mice, liraglutide attenuated the development of atherosclerosis and improved plaque stability, as measured by a change in plaque composition, specifically an increase in collagen content and alfa-smooth muscle action

The most well-known GLP-1s have demonstrated a powerful ability to protect the heart and blood vessels

POMC-derived peptides, particularly -MSH, stimulate MC1R of melanocytes, releasing the intracellular second messenger cAMP, which in turn induces a cascade of intracellular molecular events, ultimately activating the microphthalmia-associated transcription factor (MITF)