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13.7% mean weight loss at max tolerated dose over 72 weeks in SURMOUNT-5

Tirzepatide (Mounjaro for type 2 diabetes, Zepbound for weight management) is a dual GIP/GLP-1 receptor agonist licensed in the UK that typically produces substantial weight loss rather than weight gain

Another study showed that growth-releasing hormones like Ipamorelin and GHRP-6 can increase bone mineral content (BMC) by promoting bone growth and dimensions without affecting bone mineral density in adult female rats [2]