Taranta A, Bellomo F, Petrini S, Polishchuk E, De Leo E, Rega LR, Pastore A, Polishchuk R, De Matteis MA, Emma F (2017) Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells
Key advances In the SURMOUNT-1 trial for obesity, adults with overweight or obesity without type 2 diabetes mellitus achieved placebo-subtracted weight loss of up to 20% after 72 weeks of the GLP1GIP receptor co-agonist tirzepatide, with a similar safety profile to high-dose semaglutide 5
Additionally, both energy restriction and resveratrol treatment have been shown to stimulate autophagy in hepatic steatosis via a significant augmentation of autophagy-related proteins, including Beclin-1 (Milton-Laskibar et al., 2018)
A cross-sectional study of children 26 years of age concluded that frequent APAP use in these patients was associated with the formation of a wheeze or asthma (Nguyen et al., 2013)