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Melanotan II was originally designed to promote skin pigmentation, but has since been shown to induce arousal and increase body temperature in clinical settings and animal models
Gundry changed his focus to curing modern diseases via dietary changes
It means the molecule activates amylin receptors much more strongly than the closely related calcitonin receptor
Reciprocally, gut microbiota biotransform dietary components to produce various physiologically active metabolites, such as SCFAs, secondary bile acids, and indole derivatives, which enter the liver via the portal venous system and participate in host glucose and lipid metabolism as well as immune regulation ( The concept of the gut-liver-kidney nutritional metabolic axis has gradually emerged and received widespread attention in recent years
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