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These genes, encompassing both risk-associated genes for sporadic PD (e.g., SNCA , LRRK2 , GBA ) and those associated with familial forms (e.g., PARK2 , PINK1 , PARK7 ), predominantly encode proteins involved in critical cellular functions like oxidative stress response, mitochondrial quality control, and protein degradation pathways

Clinical trial data indicates tesofensine-induced weight loss consists predominantly of fat mass loss with notable preservation of lean body mass, a critical distinction from general caloric restriction which typically results in proportional loss of both fat and muscle tissue

Methylcobalamin vs cyanocobalamin B12 comes in more than one form