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The 8mg dose achieved 22.8% reduction, and even the 4mg dose reached 21.1%
The binding sites of 3G10 are mainly concentrated on the VP1 BC and GH loops and the VP2 EF loop (Fig
The stability window interacts directly with the dosing schedule, and this is a practical planning point rather than a theoretical one: at 2.4 mg/week a 10 mg vial covers four weeks, which lands exactly at the outer edge of the in-use window
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