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Biological Activity NNMTi is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50=1.2 M), selectively binding to NNMT substrate binding site residues
Enhanced local blood supply supports the metabolic demands of repair
It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+
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