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We included studies that initiate GLP-1RAs therapy in patients following bariatric surgery

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The chemistry behind the once-weekly half-life The lipid-modification strategy is the same one used for tirzepatide and semaglutide: a long-chain fatty diacid attached to a lysine side chain via a small linker, producing a molecule that binds reversibly to serum albumin and clears far more slowly than an unmodified peptide would

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