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15,16 The blood-brain barrier (BBB) is a dynamic barrier that maintains the regular physiological state and metabolism of the central nervous system (CNS), but it also inhibits peripheral drugs from entering the CNS
In addition, an insulin-sensitive GLUT4 is expressed in neurons with high energy demands, and the expression is reduced in AD brains [11, 33, 34]
GLP-1s are distinct from previous classes of prescription weight loss drugs such as phentermine, as they target essential metabolic pathways
Some pharmacies use 10 mg/mL for maintenance doses to reduce vial size
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