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Thus, in mice, hepatocyte-specific overexpression of Dpp4 is associated with hepatic insulin resistance and liver steatosis (86), whereas knockdown of Dpp4 results in improved insulin sensitivity and reduced lipid accumulation in cultured hepatocytes (95)
1 Introduction Glucagon-like peptide-1 (GLP-1RA) receptor agonists possess multiple favorable metabolic, anti-inflammatory effects and their use is associated with marked body weight reduction ( Semaglutide is a potent GLP-1RA used in the treatment of T2DM with proven cardiovascular benefits ( Multiple mechanisms have been proposed to explain the cardiovascular benefit of semaglutide
Lean proteins such as skinless poultry, fish, eggs, low-fat Greek yogurt, and legumes are ideal choices
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