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Published preclinical research on FOXO4-DRI has demonstrated selective elimination of senescent cells in mouse models, with observed improvements in fitness markers, fur density, and organ function in aged subjects
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To establish a connection with the NO-system, l-NAME (5 mg/kg intraperitoneally) (worsening) and/or L-arginine (100 mg/kg intraperitoneally) (beneficial effect) were given alone or together
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That qualitative difference matters
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How often does the DoD publish new SBIR opportunities
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