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In addition to modest inhibitory effects on DPP-4, the enzyme which eliminates GLP-1 from the body, the botanical formula improved measures of leptin resistance, promoted antioxidant activity, and attenuated mechanisms related to fat formation

Waist circumference decreasing faster than overall weight might suggest

For supplements, all you need to do is really check for safety of ingredients, that the ingredients work well together, and that there isnt some kind of a toxic reaction