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Tirzepatide is an approved, extensively studied dual agonist with a proven safety record, commercial availability, and the most comprehensive Phase 3 dataset in the GLP-1 class
Despite the promising results on ferroptosis modulators revealed by preclinical studies, the effects of sustained ferroptosis modulation on normal tissues and organs remain unresolved
No intervention needed
Enzyme activity was shown as fold changes in absorbance per minute normalized to substrates only group
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