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The decreased ratio of NAD + to NADH in the gdh3 / gdh3 mutant indicates that cofactor equilibrium may be important for the morphogenesis of C
Bax oligomerization is associated with the formation of openings in the OMM to allow the release of cytochrome c and other IMS proteins into the cytosol, and hence Bax oligomerization is considered a critical regulatory point in cell death (Youle and Strasser, 2008)
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