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Oxidative stress directly damages lipids, proteins, and DNA in lung tissues, induces an inflammatory response, and also further accelerates the pathological process by inducing iron death in lung tissues [6]

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Its worth noting that IGF1R and the insulin receptor (IR) share significant structural homology and can form hybrid receptors

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Oxidative DNA damage results in mutations that generate dysfunctional protein gene products and altered replication and transcription of crucial genes (44, 5355)

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