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Lastly, coagulation defects in cirrhosis, manifesting as petechiae, ecchymoses, or mucosal bleeding, are due to thrombocytopenia and other hemostasis abnormalities, like those seen in hematologic disorders and anticoagulant therapy for thrombotic diseases

The emerging science suggests these medications may help the heart through multiple overlapping mechanisms: weight loss plus improved vessel health, inflammation reduction, blood pressure effects, and metabolic improvements