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Excessive secretion of growth hormone (GH) by tumorigenic somatotroph cells is the cause of gigantism during childhood and acromegaly in adults, with significant morbidity due to clinical complications involving cardiovascular, respiratory, and metabolic systems
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It initiates a strong, localized healing response
The structure highlights the distinctive triple-proline motif (Pro-Pro-Pro) at positions 3-5 that contributes to the peptide's remarkable stability
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