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Data analysis In this network meta-analysis (NMA), we estimated standardized mean differences (SMD) for continuous outcomes and summary odd ratios (ORs) for dichotomous outcomes

Initial dose: 0.25 mg once weekly Increase to 0.5 mg at four weeks Potentially increase to 1.0 mg at eight weeks Maintenance dose up to 2.4 mg weekly, based on individual response Every step of the semaglutide weight loss program is watched by healthcare professionals

Inadequate nutritional intake, particularly of minerals and vitamins, can predispose individuals to muscle cramps

Weight changes are gradual and may continue over several months