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On the basis of their performance in TR-FRET assays for the detection of Munc13-4STX7 binding and their inhibitory activity on TLR9 activation in cell-based assays, we selected ENDO3 and ENDO7 for initial downstream analysis and orthogonal validation
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Studies show that sleep-deprived individuals have higher ghrelin levels (more hunger), lower leptin levels (less satiety), worse insulin sensitivity, and reduced willpower around food choices
doi: 10.1016/j.molp.2015.08.010 71 SinghY
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