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Moreover, the availability of multiple effective obesity pharmacotherapies with different mechanisms of action will provide clinicians the opportunity to select treatments based on patient preference, underlying comorbidities, medication safety profile and treatment response, with an aim to achieve the individualised WL targets, improve the overall health and/or the quality of life [7]

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Preclinical evidence suggests that acetyl-l-carnitine is endowed with antidepressive properties related to the epigenetic regulation of mGlu2 expression [32]