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Safer alternatives include optimising tirzepatide monotherapy with comprehensive lifestyle support, considering alternative approved medications such as liraglutide or semaglutide, or referral for bariatric surgery in appropriate cases

The studys primary endpoint was change in the cerebral glucose metabolic rate in the cortical regions of the brain (hippocampus, medial temporal lobe and posterior cingulate), which was not met

Youre Still Taking a Starter Dose One of the most common reasons people arent losing weight on tirzepatide is that theyre still on the introductory dose

The stomach breaks down food, and then the intestines absorb nutrients