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Combining the therapeutic approaches of GLP-1 agonists (which target extrahepatic mechanisms for metabolic disorders) with resmetirom (which target intrahepatic mechanisms for MASH and liver fibrosis) seems like a promising strategy for addressing fat accumulation, inflammation, and fibrosis associated with MASH
How do they compare on glycemic control
Earlier Phase 2 data demonstrated that at 48 weeks, participants were still losing weight with no plateau observed
CID (Collision-Induced Dissociation) CID fragments peptides by colliding them with inert gas molecules, making it widely used for routine sequencing
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