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Common eligibility criteria may include: BMI of 30 or higher BMI of 27 or higher with at least one weight-related health condition History of failed diet attempts or weight regain Appetite, cravings, or portion control challenges Metabolic risk factors such as insulin resistance, elevated glucose, high cholesterol, or hypertension Need for physician-supervised weight loss due to medical complexity Eligibility must be determined through a medical consultation

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While carnitine supplementation could have benefits, some recent studies suggest that chronic oral L-carnitine administration may be associated with an increased risk for atherosclerosis via increased trimethylamine (TMA) and/or trimethylamine N-Oxide (TMAO) levels (54, 55)