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Mechanism: GHK-Cu modulates over 4,000 human genes approximately 6% of the human genome
Folkert, I, Mehran, RJ, Sun, R, Morris, VK, Overman, MJ, Kee, BK, Antonoff, MB , Tzeng, CW, Dasari, NV, Tran Cao, HS, Parseghian, C, Vilar Sanchez, E, Willis, JA, Newhook, TE, Hofstetter, WL, Kopetz, S, Vauthey, JN, Chun, YS
The split-dosing approach (3x weekly vs once weekly) is described as maintaining more consistent hormone levels and reducing peak-related side effects
These oocytes exist in dormant follicles until activated by cyclical hormone signals after puberty
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