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Due to the compounds plasma half-life of approximately 3.86.9 hours [4] , twice-daily (BID) dosing may provide more sustained NNMT inhibition
However, there are also cases when additional factors such as lack of sleep, poor diet, and deficiency of other vitamins like iron, folate, and others, contribute to the issue
The single principle that makes every calculation below work is this: concentration is drug divided by water
This is helpful in cases where patients have multiple vitamin deficiencies
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