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In addition, these medicines stimulate the pancreas to produce insulin, allowing the body to convert ingested food into energy and reduce the amount of glucose in the bloodstream

For instance, exenatide, the first GLP-1-analogue developed, demonstrated to promote human monocyte differentiation into alternatively activated M2 macrophages, leading to an increase in anti-inflammatory cytokines such as IL-10 while significantly reducing pro-inflammatory cytokines, including IL-6, TNF- and IL-1 ( Furthermore, GLP-1 has been hypothesised to act as a mediator between innate and adaptive immune responses

Nutrients 12 (5), 1389

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