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Unlike traditional erectile dysfunction agents, PT-141 works through the central melanocortin pathway rather than vascular smooth muscle, making it unique for investigating sexual response and psychogenic arousal 2,4
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Obesity disrupts bone metabolism and leads to increased bone resorption, but GLP-1RAs can inhibit this damage and improve bone health by increasing the OPG/RANKL ratio, reducing osteoclast activity, and promoting bone formation
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