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ACOG Committee Statement No
The most 3 TSS gives rise to the shorter, major message (GSTF8-S) that is much more stress-responsive than the longer transcript (GSTF8-L) originating from an upstream TSS, which encodes the larger form of the protein
Oral supplements or injections both show strong effects during this period
This multi-modal strategy costs less than repeated professional-only treatments producing superior long-term outcomes versus topical-only protocols potentially producing incomplete results in moderate to severe cases
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