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Pharmac Ther
Although significant knowledge gaps remain regarding the full scope of KYN metabolites, those produced downstream of KMO are generally regarded as neurotoxic and have been implicated in psychopathology
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Concurrently with the shedding process, re-epithelialization of the lamina functionalis is initiated by increasing levels of E2, along with the expression of its target genes estrogen receptor 1 ( ESR1 ) and progesterone receptor ( PGR ) (Fig
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