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Description

The robust weight loss combined with a well-tolerated safety profile reinforces our confidence in the clinical development programme [of CT-388] as we advance to phase III trials" Dr Levi Garraway, PhD, Roches Chief Medical Officer and Head of Global Product Development, said: We are pleased to see such meaningful weight loss in people treated with CT-388

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3.3 Bidirectional host-microbiota feedback shaped by BAs BAs serve as central mediators in a dynamic bidirectional dialogue between the host and its gut microbiota, wherein host-derived BAs shape microbial composition, and microbial-modified BAs, in turn, regulate host gene expression and immune function

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