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The findings were reassuring enough that, in January 2026, the Food and Drug Administration (FDA) requested the removal of suicidal ideation and behavior warnings from the labels of GLP-1s, including Wegovy and Zepbound, after reviewing the available evidence

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This article explains Retatrutide weight loss results trial data and FDA status, including how it may work, what trial results showed, possible side effects, and why medical guidance matters before starting any weight-loss plan