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Relative contraindications and special populations requiring careful consideration: Patients with severe hepatic impairment (Child-Pugh class C) should generally avoid these medications due to insufficient safety data
(2010) 125:S7380
Secondary endpoints were the percentage of patients attaining 5, 10, 15, and 20% weight loss and improvements in metabolic, cardiovascular, and comorbidities after 12 months of follow-up
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