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(3) Bes F, Hofman W, Schuur J, Van Boxtel C

Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets

B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve