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& Compston, J
A GLP-1 pill offers a chance to push that progress even further if we can figure out how to expand access and how to better support patients so they can lose weight in a healthy way
But sales never took off the drugs were too expensive, the pills were too large, and there were questions about the drugs safety
A peak serum concentration of 0.22 g/mL was observed 1 h after oral administration at a dose of 1.0 g/kg in a mouse model, while a peak concentration of 2.25 g/mL was recorded 0.25 h after intraperitoneal administration at the same dose (Pan et al., 1999)
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