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PPG-YFP 17 mice were bred in-house (UCL, London) on a C57BL/6 J background and fed a regular chow diet (Teklad 2018 or 7912, Envigo) ad libitum
Previous allergic history represents an important consideration
We recently identified the FOXO4 p53 axis as pivotal in maintaining the viability of senescent cells, and that senescent cells can be targeted selectively with the senolytic peptide FOXO4-DRI
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