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They play critical roles in controlling blood sugar, but their impact on appetite and satiety is profound
Beneficial effects have also been studied in overweight or obese non-diabetic individuals
Similarly, in LDL receptor knock-out mice subjected to a Western diet, treatment-reduced plaque lesions and semaglutide were reported to affect the expression of several genes related to cholesterol metabolism, leukocyte recruitment, adhesion and extravasation, and also extracellular matrix protein turnover [35]
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