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Patients with a personal or family history of medullary thyroid carcinoma represent another critical contraindication for tirzepatide-containing formulations
transport (DDP/DPU)
doi: 10.1056/NEJMoa1109400 158 ObeidRAwwadHMRabagnyYGraeberSHerrmannWGeiselJ
BPC-157 is described as well tolerated and without demonstrated toxicity in rodents, but the human safety dossier is unpublished, and over 80 percent of the literature comes from a single research group, so independent replication is limited Sikiric et al., 2025
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