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Nutritional Needs During Treatment Suppressed appetite is the medications intended effect, but it creates challenges for adequate nutrition
Additionally, data from a Phase I clinical trial (NCT02861300) indicated that the combination of CB-839 and capecitabine which is a prodrug of 5-FU, was well tolerated by CRC patients at bioactive doses
Rapid weight gain of more than 3-5 pounds within a few days, particularly when accompanied by shortness of breath, leg swelling, or abdominal distension, may indicate fluid retention related to cardiac or renal dysfunction
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