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In addition, hyperandrogenism by itself stimulates the deposition of adipose tissue in the visceral area, with further increase in insulin resistance, thus contributing to the vicious circle [17]
9 Environmental and epigenetic factors Environmental exposures, including endocrine-disrupting chemicals (EDCs), have been increasingly implicated in PCOS risk and phenotype expression (31)
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BMI requirements were increased to greater than 40 mg/kg2 or greater than 35 mg/kg2 with one more weight-related comorbidity
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