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Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]
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Creatine deficiency has been shown to reduce energy production via the electron transport chain (Nabuurs etal, 2013)
Tirzepatide with niacinamide is a new, powerful tool for weight loss and metabolic health
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