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IGF-1 LR3 functions through direct, sustained agonism of the IGF-1 receptor (IGF-1R), a receptor tyrosine kinase, activating the same downstream intracellular signalling cascades as native IGF-1 but with substantially reduced IGFBP-mediated attenuation and a far longer biological activity window

R., Cho, H

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GLP-1 receptor agonists are a class of medications that mimic the action of glucagon-like peptide-1, a naturally occurring hormone produced in the intestine